HumansareCapableofGreatness
Capable turns frontier intelligence into frontier medicines.
Our Team
Isaak
Freeman
Freeman
Helena
Rose
Rose
George
Church
Church
Melissa
Du
Du
Gregory
Bird
Bird
Nicolas
Pellier
Pellier
Bradley
Pentelute
Pentelute
Stephen
Goldstein
Goldstein
Alana
Pickett
Pickett
Farbod
Salahi
Salahi
Luis
de Lecea
de Lecea
Backed with $50M by
Wojciech Zaremba
Co-founder, OpenAI
Srinivas Narayanan
prev. CTO, B2B Applications, OpenAI
Kevin Weil
prev. CPO, OpenAI
Fidji Simo
prev. CEO of Apps, OpenAI
Joe Betts-LaCroix
Founder & CEO, Retro
Daniel Liu
Anthropic MTS
Julian Schrittwieser
Anthropic MTS
David Dohan
Anthropic MTS
Andrej Karpathy
Anthropic MTS
Kayla Leung
Adam Jonas
Adam Canady
Chris Leiter
Kevin Vilkin
Annie Case
Saturnin Pugnet
Jacob Buckman
Shyamal Anadkat
Riley Walz
Mehran Jalali
Peter Diamandis
Anne Lee Skates
Tyler Cowen
Elizabeth Weil
Anne Brandes
Michael Retchin
Rahul Arora
Will DePue
Philip Bogdanov
Justin Mares
Adam Draper
Gus Domel
Brayton Williams
Winnie Qiu
Amol Sarva
Inaki Berenguer
Trevor Chow
Michael Florea
Max Marchione
Larsen Jensen
Riley Loftus
Alexey Guzey
Moritz Baier-Lentz
Vas Bailey
Jonathan Lachman
Tim Rocktäschel
Vincent Weisser
Context
In the age of ever-improving AI capabilities, we humans are lagging behind.
We're hungry, distractable, and tired.
Roughly half of us will get cancer or heart disease. We fall ill.
A third of our day is spent asleep.
The modern world feeds us slop that leads even further down the drain.
We believe that humans are capable of more.
Nature gave us clues on making this dream real. Research has given us insight into thousands of powerful rare variants.
Program 1/4
Ozempic for Sleep
We spend a third of our lives asleep. Yet, a small subset of humans thrive on four to six hours of sleep per night. They carry short sleeper variants, allowing them to remain healthy while being awake for longer. Previous research reports those short sleepers to have more energy, vigor, and disease resistance. While not definitive evidence, we see them as a proof-of-concept for our biggest frontier for improving human health.
Our first four programs are in sleep. Concretely, we are first working on therapeutics that restore cognitive performance under sleep deprivation, and then towards the end-goal of allowing patients to sleep 1-2 hours less. Our initial focus will be on rare, undertreated sleep diseases like narcolepsy and hypersomnia, while gradually expanding to a broader population, via shift-work sleep disorders.
Our Flagship Therapeutic
The world's most successful drug is a peptide: In 2025, Tirzepatide made $36B.
What's the model that will design the next Tirzepatide?
We’re building a vertically integrated, AI-enabled, deeptech platform to rapidly explore and unlock new human capabilities.
Frontier models won’t be bottlenecked by intelligence. They’ll be bottlenecked by the speed of data and active learning.
The Engines of Creation
SynthesisSPPSStep 1/7
Making peptide and nucleotide therapeutics rapidly with automated polymer synthesis.
Humans are Capable
Of having more energy on less sleep
Of having more energy on less sleep
of having more endurance
of being more immune to viruses
of smelling like flowers
of less neurodegeneration with age
of living longer lifespans
of having unbreakable bones
Of having more energy on less sleep
of having more endurance
of being more immune to viruses
of smelling like flowers
of less neurodegeneration with age
of living longer lifespans
of having unbreakable bones
Of having more energy on less sleep
of having more endurance
of being more immune to viruses
of smelling like flowers
of less neurodegeneration with age
of living longer lifespans
of having unbreakable bones
Capable turns frontier intelligence into frontier medicines.